Sperm DNA fragmentation

Sperm DNA fragmentation

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. It is an honour to write the foreword to this focused issue of TAU on sperm DNA fragmentation (SDF). From my time as a first generation embryologist in the early days at the University of Cambridge with Professor Robert Edwards and in my current role at the London Women’s Clinic, I have become acutely aware of the num...

Sperm DNA fragmentation testing

The editors of this book, Drs. Ashok Agarwal, Ahmad Majzoub, Chak-Lam Cho and Sandro Esteves, are to be congratulated for bringing together an extensive tome on the evaluation and management of sperm DNA fragmentation. The perspectives from North America, South America, Europe, Asia and the rest of the world provide an interesting snapshot into management of the unique phenomenon of sperm DNA d...

Understanding sperm DNA fragmentation

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. We greatly value the commentary by Dr. Gosalvez on the “Clinical utility of sperm DNA fragmentation testing: practice recommendations based on clinical scenarios” by Agarwal et al. (1). The author initiated his well-written note with an overview of the structural and physiologic significance of sperm DNA on male repro...

Sperm DNA fragmentation

tau.amegroups.com © Translational Andrology and Urology. All rights reserved. I agree with Agarwal et al. (1) that sperm DNA fragmentation (SDF) should be included in the evaluation of male factor infertility, along with semen analysis. Although there exist divergent views on this topic, our group has routinely employed SDF (TUNEL assay) and other methods for identification of sperm DNA damage ...

Evidence based sperm DNA fragmentation